Figures Figures Front Cover: Layer 5 pyramidal neurons of the human cerebral cortex stained using the rapid Golgi silver impregnation method, courtesy of William W. Seeley, MD Front Cover: Jerry and Cindy, courtesy of the author Pg V: Cindy and Bruce’s travels through North America. Light gray footsteps are Cindy’s. Dark gray footsteps are Bruce’s. Gray lines are Cindy’s visits to her father, Jerry. Drawing by Caroline Prioleau Pg VI: Key parts of the cerebral cortex. Drawing by Caroline Prioleau Pg 16: Congratulatory letter to Cindy, informing her of her upcoming participation in Wheel of Fortune’s 1986 “College Week” Pg 24: Different brain disorders that lead to the symptoms of dementia.Drawing by Caroline Prioleau Pg 27: Normal hippocampus (left); hippocampus with neurofibrillary tangles staining dark (center); amyloid plaque (right). Plaques and tangles are the pathological hallmark of Alzheimer’s disease. Courtesy of Salvatore Spina, MD, PhD, of the UCSF Neurodegenerative Disease Bank Pg 29: The spread of the misfolded form of the protein tau along functional networksdue to Alzheimer’s disease. Illustration courtesy of Cathrine Petersen Pg 35: Cindy’s eulogy at Jerry’s 1997 funeral Pg 38: Two of the letters Cindy wrote to Jerry (years unknown) Pg 53: Cindy’s maternal grandmother, Sarah (year unknown) Pg 65: Source: Images from Zachary A. Miller, Maria Luisa Mandelli, Katherine P. Rankin, et al., “Handedness andLanguage Learning Disability Differentially Distribute in Progressive Aphasia Variants,” Brain. 2013;136/11,3461–73, by permission of Oxford University Press. Pg 67: An example of the loss of semantic details. The animals all start to look alike and have only rudimentarycharacteristics specific to their genus (if they have themat all). Illustration typical of numerous patient files.Drawing by Caroline Prioleau Pg 79: Jerry in Las Vegas, 1986 Pg 87: Jerry playing golf (year unknown) Pg 113: Cindy at home with her dog, Tocca, in Verona, New Jersey (year unknown) Pg 139: Letter from Jerry to Cindy dated February 22, 1984 Pg 143: Jerry (“The Machine”) playing basketball (year unknown) Back cover: The Life and Death of Billy Miller, a watercolor by Harriet Bernice Sanders Miller, MFA,courtesy of Bruce L. Miller, MD